History

Six & Twenty Distillery is located in West Greenville, South Carolina. The name Six & Twenty is carried by a beautiful love story about a Choctaw woman, Isaqueena, an English merchant, and a bold escape. According to the story, Isaqueena rode across the land to save her beloved from a Cherokee attack, and hence the name Six & Twenty is a tribute to this legend. The distillery describes its original location as part of the land where the story took place, and they promise a passionate effort to create the best local spirits, handmade with heart and soul. Their message of being driven by 'a labor of love' is reflected in a reference to carefully supervised and gently cared-for batches, barrels, and bottles.

Six & Twenty also presents itself as a place where there is a culture of local craftsmanship, and where they blend grain and glass through a grain-to-glass approach.

Production

The distillery follows a grain-to-glass approach with mash, fermentation, distillation, aging, and bottling on site. They highlight the use of locally grown grain and their own designed Artisan Still, which underpins their spirits production. They describe themselves as a craft-destination where you mash, ferment, distill, age, and bottle – all under one roof. Their Still House and Cocktail Bar form a central part of the experience, and they communicate an ambition to be South Carolina’s premier craft distillery.

Products / Whisky Series

Old Money Wheat Whiskey — a wheat-based whiskey aged in American barrels for about three years. Notes: On the nose there are vanilla and maple; the palate is smooth with notes of caramel, vanilla, and maple.

5-Grain Bourbon — the world's first 5-grain bourbon; grain bill includes corn, wheat, barley, Black Seashore Rye and Carolina Gold Rice; aged 3 years in brand-new American oak barrels. Notes: Smoke, spice and sweetness; Taste: cinnamon, vanilla, and black pepper.

Avena Oat Whiskey — whiskey made from oats as the grain; Grain Bill: Avena Oat. Nose: oatmeal and brown sugar. Taste: oats, brown sugar, and a buttery finish.

Heirloom Rye Whiskey — limited release; Nose: sweet, nutty; Taste: wafers (crisping), caramel and bread pudding.

These products illustrate Six & Twenty’s range of white or clear spirits and their unique grain blends, with a focus on grain-to-glass and craftsmanship.

Visiting / Experiences

The Tasting Room & Cocktail Bar are open Monday–Thursday 12:00–20:00 and Friday–Saturday 11:00–22:00 (bottle sales end at 19:00). Guests can also join self-guided tours through the distillery.

Tastings/Guided Tours: Grain-to-Glass tours normally take place on Saturdays at 12:00, 14:00 and 16:00 (note: book online). Price for a distillery tour is 20 USD and lasts about 1 hour. Private distillery tours are available for groups of 10+ people (about 1 hour, 45 USD).

Cocktail classes offered as an experience (65 USD). In addition, there are virtual events where participants receive a packaged tasting set to take home and can join in on a tour and tasting or mixology class. There is also the option to fill your own bottle from selected products (e.g., Cask Strength Old Money or 5-Grain Bourbon).

Opening hours and events (updates and bookings) can be reserved online via the distillery's site.

Philosophy

Six & Twenty focuses on locally produced spirits and the “Grain to Glass” philosophy: they mash, ferment, distill, age, and bottle on site with their own designed Artisan Still. They emphasize the use of locally grown grain and a handcrafted approach, where each batch is treated with care and love. Their bar program is limited to the spirits they produce, and they offer customized cocktail menus for events and gatherings. The distillery is located in West Greenville and presents a close connection to local craftsmanship and culture, as part of its identity as South Carolina’s premier craft distillery.